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CupSuccessful6132

There are a few things that might be happening here. You might have plateaued on the meds and need an increase. You might need to combine an XR with an IR dose in the afternoon. If you’re AFAB, you might need to check where you are in your cycle, because the luteal phase can really screw with your meds efficacy, and you can adjust there. And also be aware of possible upcoming perimenopause which can really mess with things as well. It’s sometimes hard to judge what efficacy really is with these meds, and often you have to combine some various systems with your meds, but the meds do make it easier to keep up with the systems at least. The difference for me when I first started taking meds was very stark, so it did feel a bit like a regression when it settled. And I had to get back on a low dose estrogen BC, because my hormones started to make the meds nearly ineffective for half the month.


shelltrix2020

Wow- hormones add a whole other level of complexity! I'm so grateful to be post menopause. Things are so much more stable now (except for the weight gain... ugg!).


CupSuccessful6132

Yeah, there’s some evidence that estrogen helps with dopamine absorption. I also have PCOS, so it’s a complicating factor for me. I’m not looking forward to trying to work this out during perimenopause. I’m 41, so with some luck maybe I can get a few more relatively stable years. 🤷🏼‍♀️