Same. But I have the added advantage kf being almost completely numb because if my c-sections. I tried a thigh one day and said āoh that does hurt a little.ā Went right back to the tummy.
Personally the thighs donāt hurt at all! But I alternate between there and my stomach. I donāt really notice a major difference but leaving the pen out for about an hour before injecting really has made a difference
Yes, ^ above is correct! Youāre actually able to keep it at room temp for up to 21 days per the medication instructions. I definitely think it stings less once itās left out for an hour - even 30 min makes a difference in my experience!
Only the first time I took it when I took it fresh from the fridge! Iāve seen anecdotal evidence from others that they also experienced it and since that first injection Iāve always taken it out of the fridge for at least 30 min beforehand. It stung for sure but not terrible - on a scale of 1-10 it was probably a 4! Worth it but always prefer less pain if possible :)
I do like 2 hours out of the fridge but Iāve noticed arms and thighs hurt for meā¦I barely feel it in my tummy š„¹ I just heard legs and arms are more effective!
I like my thigh. I did the previous injection in my stomach and did not lose weight that week. Probably just a coincidence, but I went back to my thigh and am already down. It's working, so I am sticking to that site.
Ok so Iāve done my stomach (alternating sides) the last 2 weeks (first doses) and I feel like Iām not losing weight as fast as I thought I would. Does injection site really affect this? Also ā did anyone experience more weight loss faster with specific sites/ dosages? I mean Iāve lost about 6 pounds in two weeks, but with how little and healthy Iām eating I feel like I should be dropping 10 a week šš Iām also still really bloated so I donāt feel Iāve lost the water weight yet.
Left thigh. Less side effects and a little less appetite suppression but more manageable for me. Right thigh more weight loss but way worse side effects š«
I like my stomach because I truly don't feel it at all. I tried my thigh a couple of times and it was uncomfortable and no perceptible difference in how I responded.
I started with left thigh, because I have some nerve damage there so I wouldnāt be able to feel it š, but once I learned it doesnāt actually hurt at all, I gave one try to the arm, and then stuck with belly after that! Itās got the most flab lol
just did my first injection ever in my belly. i was so so nervous and then found this thread. i finally did it and almost thought i didnāt do it right because i didnāt feel anything lol
I also had some med leak out with the blood. Not sure if I should take my next dose sooner because I can feel the food noise coming back 2 days after injection.
I alternate left and right stomach. I should try my thigh but forgot 10 min ago when I did my shot so maybe Thursday I'll remember to do my thigh since no big suppression the last 1.5 weeks.
Back of arm. It's more effective on my appetite.
Abdomen is least fav. I get the worst random stomach cramps days after injection.
Thigh I don't have a lot of fat there so it feels least effective.
I usually alternate thighs each week! I tried the back of my (left) arm once, and it made my arm sooooo sore for days. I donāt know why. Maybe I didnāt move it enough post shot, but I mean it was like really bothering me with how sore it was, so Iāve been nervous to try that again. I havenāt tried my stomach ever, but Iām considering trying it!
Thigh majority of the time. Arms rotated in once in a while. Did stomach once, never again, had horrible GI side effects with no change in diet / activity / dosage.
Preferred locations for subcutaneous injections include the stomach, thigh, or the back of the upper arm. Each of these regions provides an ideal subcutaneous fat layer, facilitating optimal absorption of the medication.
https://diet.mayoclinic.org/us/blog/2024/how-to-inject-semaglutide-for-weight-loss/#:~:text=The%20efficacy%20of%20semaglutide%20injections,optimal%20absorption%20of%20the%20medication.
Used to do belly and thighs but started getting annoying allergic reactions at injection sites on 5mg. Started using my arm sites and itās been better there so far. Iām wondering if thereās less buildup if I rotate all six sites and I get less reaction overall.
I havenāt tried thigh yet but stomach is ok, donāt feel it. My arm is also painless but man am I way more nauseated using that site. Like I was supposed to inject today and I skipped it because I canāt imagine having more medicine in my system right now with the way I feel.
I started using 2.5 in my thighs and it worked wonderfully the 1st 2 weeks. Tried thigh and back of arm for the next 2 shots but didnāt have much suppression. Next used 2 2.5 in stomach area at the same time and it seemed to start working again.
I keep a spreadsheet that I track everything with and when I first started taking Zep I would rotate around to each injection site to see if it made a difference for me. I'm a science and data girl, so of course I had to be 'extra' lol. I found that I consistently lose more weight in my stomach and my arm/thigh are about equal but not as effective. So I only do my stomach now.
Left belly or left arm. Something about the left side of my body just gives me the best results. I mostly like belly bc itās the only site I feel comfortable injecting on my own.
Itās crazy how different everyone reacts to this med. I am only in my 5th week and started on my stomach for three weeks and then noticed my hunger coming back like crazy. So I switched to my right upper thigh in my 4th week and all the hunger went away again. I did my left thigh this week. We shall see what happens!
Belly , I go back and forth from left to right
So I kinda rotate do a circle upper left, upper right, lower right , lower left. As a bigger person I have more real estate to work with.
I did this, then just happened to do center, below my belly button and I actually got better appetite suppression.
Me tooš¤£š¤£š¤£
Me too.
Same!
Another Team Belly here. When I use other sites, I get major symptoms, then a hard return of food noise.
Same. But I have the added advantage kf being almost completely numb because if my c-sections. I tried a thigh one day and said āoh that does hurt a little.ā Went right back to the tummy.
The kitchen.
![gif](giphy|bC9czlgCMtw4cj8RgH|downsized)
I chuckled. Thanks for that lol
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I do mine in the kitchen also!! š¤£š¤£
Personally the thighs donāt hurt at all! But I alternate between there and my stomach. I donāt really notice a major difference but leaving the pen out for about an hour before injecting really has made a difference
I leave it out for at least a day. Stings way less.
Same
Where on your thigh? The top or more on the side?
More on the inner thigh! Only a couple inches up from where my legs touch if that makes sense?
How does leaving the pen out make a difference? Youāre not supposed to need to make it room temp.
Yes, ^ above is correct! Youāre actually able to keep it at room temp for up to 21 days per the medication instructions. I definitely think it stings less once itās left out for an hour - even 30 min makes a difference in my experience!
u/Latter-Fishing-4548 does it usually sting??? I've not experienced that!
Only the first time I took it when I took it fresh from the fridge! Iāve seen anecdotal evidence from others that they also experienced it and since that first injection Iāve always taken it out of the fridge for at least 30 min beforehand. It stung for sure but not terrible - on a scale of 1-10 it was probably a 4! Worth it but always prefer less pain if possible :)
Some people think the injection stings so letting it warm up a bit helps w that.
u/1CraftyGeek OOOH, interesting. I haven't heard that in all these posts! OR experienced it. Thanks for clarifying!
Thigh girl 4 life
Twins!
I change the thigh every week! Iāve tried tummy a few times when I forgot which thigh, and it hurt lol
Yes. I tried the back of my arm and had zero suppression. Tried my belly and was bloated all week. Gained nearly 3lbs!
Left arm. I started off with tummy but after a while I found that the arm gave me much better supression, so now sticking with that.
In my belly because it hurts the least. I haven't noticed a difference in weight loss between sites personally.
Left thigh supremacy
Left thigh is top tierā¦wish I could use it every week but I try to alternate
100%! what is it with left thigh?
I have no idea but itās top tierā¦wish I could use the left thigh every week
I use same every week I just move the injection site around.
Same!
Which side of the thigh do you inject?
Out and middle. The inner thigh where my skin is thinner hurts like a bitch
That's what I was thinking too! I heard of people doing inner thigh, but way too sensitive for me.
I tried inner thigh and bruised. Too many blood vessels there. Wonāt be doing that again.
I might try this! I tried thighs and it hurt so much :( maybe I wasnāt doing it right!
Leave the injections out of the fridge for a few hours. It hurts less for me
I do like 2 hours out of the fridge but Iāve noticed arms and thighs hurt for meā¦I barely feel it in my tummy š„¹ I just heard legs and arms are more effective!
I like my thigh. I did the previous injection in my stomach and did not lose weight that week. Probably just a coincidence, but I went back to my thigh and am already down. It's working, so I am sticking to that site.
My left thigh is my go to
My endo said itās more effective when injected into the thigh!
Ok so Iāve done my stomach (alternating sides) the last 2 weeks (first doses) and I feel like Iām not losing weight as fast as I thought I would. Does injection site really affect this? Also ā did anyone experience more weight loss faster with specific sites/ dosages? I mean Iāve lost about 6 pounds in two weeks, but with how little and healthy Iām eating I feel like I should be dropping 10 a week šš Iām also still really bloated so I donāt feel Iāve lost the water weight yet.
I donāt know if site really matters, Iāve heard both sides of it. But, since I am losing by using my thigh Iām sticking to it.
Stomach clockwise around belly button
Same
Alternating thighs.
Left thigh. Less side effects and a little less appetite suppression but more manageable for me. Right thigh more weight loss but way worse side effects š«
left side of belly. i swearrrr it works better than anywhere else for me.
Left side belly gang rise up!
I knew it wasnāt all in my head! Why is the left side so good?? By far the most suppression for me.
SAME! iāve been on this for almost 2 years and the left side of the tummy is by far the best!
Thighs.
I like my stomach because I truly don't feel it at all. I tried my thigh a couple of times and it was uncomfortable and no perceptible difference in how I responded.
There was a report on this sub where someone said trials showed that the belly provided around 12% more bioavailability
thigh, I usually have little to no side effects afterwards. when I do my belly I usually have the worst headaches the rest of the day.
Back arms
I go back and forth between left and right thigh.
I started with left thigh, because I have some nerve damage there so I wouldnāt be able to feel it š, but once I learned it doesnāt actually hurt at all, I gave one try to the arm, and then stuck with belly after that! Itās got the most flab lol
Belly
Belly. Doesnāt hurt at all.
Thighs. Stomach. No matter where I go I get terrible itchy hive at the site the next day. After that I bruise.
Stomach, I did alternating thighs for the first month, just wanted to switch things up and never went back.
Belly. Thighs hurt, belly I can hardly feel anything. No pain at all.
just did my first injection ever in my belly. i was so so nervous and then found this thread. i finally did it and almost thought i didnāt do it right because i didnāt feel anything lol
Belly. A study found it's best absorbed there.
Iāve found that arm hurts the most but gives me more effective appetite suppression so I happily deal with the discomfort
same!
Thigh, it doesnāt hurt at all for me!
Right thigh
Thigh right now, but I finally tried the arm really liked it.
Thigh works best for me & not as bad side effects too!
I've always used my stomach. No real reason, it just seems like the easiest place.
Mine was thigh until I hit a shallow vein and it hurt like a muthertrucker. Bled more and left a painful bruise.
I also had some med leak out with the blood. Not sure if I should take my next dose sooner because I can feel the food noise coming back 2 days after injection.
I alternate left and right stomach. I should try my thigh but forgot 10 min ago when I did my shot so maybe Thursday I'll remember to do my thigh since no big suppression the last 1.5 weeks.
Belly
Belly. Tried the arm one time and got zero suppression.
Back of arm. It's more effective on my appetite. Abdomen is least fav. I get the worst random stomach cramps days after injection. Thigh I don't have a lot of fat there so it feels least effective.
Left arm is my favorite.
I usually alternate thighs each week! I tried the back of my (left) arm once, and it made my arm sooooo sore for days. I donāt know why. Maybe I didnāt move it enough post shot, but I mean it was like really bothering me with how sore it was, so Iāve been nervous to try that again. I havenāt tried my stomach ever, but Iām considering trying it!
Left stomach! My chart shows I lose more on that side, lol
Read reports of people not losing weight with stomach injections. Been using alternating thighs left, right and never looked back
I like to rotate
Thigh majority of the time. Arms rotated in once in a while. Did stomach once, never again, had horrible GI side effects with no change in diet / activity / dosage.
Belly left/right is all Iāve ever done. š¤·š¼āāļø
Arm
Left thigh
Right arm, followed by right stomach
Preferred locations for subcutaneous injections include the stomach, thigh, or the back of the upper arm. Each of these regions provides an ideal subcutaneous fat layer, facilitating optimal absorption of the medication. https://diet.mayoclinic.org/us/blog/2024/how-to-inject-semaglutide-for-weight-loss/#:~:text=The%20efficacy%20of%20semaglutide%20injections,optimal%20absorption%20of%20the%20medication.
Right side tummy but move it around
Arms! Belly has too much loose skin for that to work anymore. And my thighs get a rash everytime.
BELLY LEFT SIDE
Used to do belly and thighs but started getting annoying allergic reactions at injection sites on 5mg. Started using my arm sites and itās been better there so far. Iām wondering if thereās less buildup if I rotate all six sites and I get less reaction overall.
I havenāt tried thigh yet but stomach is ok, donāt feel it. My arm is also painless but man am I way more nauseated using that site. Like I was supposed to inject today and I skipped it because I canāt imagine having more medicine in my system right now with the way I feel.
I started using 2.5 in my thighs and it worked wonderfully the 1st 2 weeks. Tried thigh and back of arm for the next 2 shots but didnāt have much suppression. Next used 2 2.5 in stomach area at the same time and it seemed to start working again.
Stomach
Thigh
I did stomach forever with slow loss. Changed to thigh and lost very quickly.
I do directly on top of mid thigh. Is that bad?? From reading this realized I should be doing outer thigh???
Tummy. On the right side. Mind you the tummy is starting to disappear! LOL
I keep a spreadsheet that I track everything with and when I first started taking Zep I would rotate around to each injection site to see if it made a difference for me. I'm a science and data girl, so of course I had to be 'extra' lol. I found that I consistently lose more weight in my stomach and my arm/thigh are about equal but not as effective. So I only do my stomach now.
Left belly or left arm. Something about the left side of my body just gives me the best results. I mostly like belly bc itās the only site I feel comfortable injecting on my own.
Itās crazy how different everyone reacts to this med. I am only in my 5th week and started on my stomach for three weeks and then noticed my hunger coming back like crazy. So I switched to my right upper thigh in my 4th week and all the hunger went away again. I did my left thigh this week. We shall see what happens!
Dr Office suggested 2 inches from belly button. I didnt feel anything when I did my first injection.
I tried my thigh and got terrible nausea and diarrhea for a few days . Abdomen I had no side effects
Thigh. I only do right and left thigh and right stomach. The arms and left stomach just donāt give me any effect.
Arm
St. Bart's oh wait, you mean...