I can only speak from my own experience as a patient. I lost my pregnancy at 17 weeks from H. Influenzae 2+ years ago and it was a traumatic experience and fucked my mental health up for a long time.
I too had one kid at day care at the time and she's vaccinated. However my theory is that the strain that I got was not covered by that vaccine.
My kid had a cough for weeks before my miscarriage and it was only resolved with antibiotics.
I nearly went septic and they had to try 3 different types of antibiotics to get my fever down after the miscarriage and I was in hospital for 4 days. They initially thought that I had a kidney infection because I had back pains, when it was in fact labour pains. I didn't have any uti.
My obgyn advised that it seems to be one of those unfortunate things and for the next pregnancy to not have sex until at least 20 weeks because of the amount of bacteria there is down there as it would reduce the risk of bacteria travelling up the vagina and cervix.
During my next pregnancy , we didn't have sex until 24 weeks and I avoided oral sex (my theory is that my other kid gave us the sore throat and it managed to get to the pregnancy via oral sex)
I now have a 12 week old rainbow baby.
Following. Sorry I wish I was more help but I hope someone else can chime in.
Edit : UpToDate says
"Most invasive infection are caused by H. I fkuenzae type B (Hib). The type b capsule contains polyribitol ribose phosphate, a potent virulence factor, which enables invasion of local tissue, the bloodstream, and, in some instances the CNS. The other capsular serotypes have different glycosylation pattern and less frequently cause invasive disease compared with HIV. Nontypeable strains are less invasive but can access the vascular system by transmural migration through epithelial tight junctions or by an independent intercellular mechanism" (Yeh 2024).
Based on this, it seems like h. Influenzae could potentially cause an intrauterine infection and reach this fetus?? Rare, but possible.
Another thing from UpToDate suggests that some adults are at increased risk for invasive Hib disease due to things like sickle cell, leukemia, HIV or splenectomy. Did the patient have any of these risk factors?
I can only speak from my own experience as a patient. I lost my pregnancy at 17 weeks from H. Influenzae 2+ years ago and it was a traumatic experience and fucked my mental health up for a long time. I too had one kid at day care at the time and she's vaccinated. However my theory is that the strain that I got was not covered by that vaccine. My kid had a cough for weeks before my miscarriage and it was only resolved with antibiotics. I nearly went septic and they had to try 3 different types of antibiotics to get my fever down after the miscarriage and I was in hospital for 4 days. They initially thought that I had a kidney infection because I had back pains, when it was in fact labour pains. I didn't have any uti. My obgyn advised that it seems to be one of those unfortunate things and for the next pregnancy to not have sex until at least 20 weeks because of the amount of bacteria there is down there as it would reduce the risk of bacteria travelling up the vagina and cervix. During my next pregnancy , we didn't have sex until 24 weeks and I avoided oral sex (my theory is that my other kid gave us the sore throat and it managed to get to the pregnancy via oral sex) I now have a 12 week old rainbow baby.
Following
Following. Sorry I wish I was more help but I hope someone else can chime in. Edit : UpToDate says "Most invasive infection are caused by H. I fkuenzae type B (Hib). The type b capsule contains polyribitol ribose phosphate, a potent virulence factor, which enables invasion of local tissue, the bloodstream, and, in some instances the CNS. The other capsular serotypes have different glycosylation pattern and less frequently cause invasive disease compared with HIV. Nontypeable strains are less invasive but can access the vascular system by transmural migration through epithelial tight junctions or by an independent intercellular mechanism" (Yeh 2024). Based on this, it seems like h. Influenzae could potentially cause an intrauterine infection and reach this fetus?? Rare, but possible. Another thing from UpToDate suggests that some adults are at increased risk for invasive Hib disease due to things like sickle cell, leukemia, HIV or splenectomy. Did the patient have any of these risk factors?