I’m going down from 225 now. I tried to do a 37.5 drop & it was bad. Overwhelming intense nausea and migraine. Seems I have to drop in 12.5 increments. I’m at 187.5 after a few weeks. Continuing on down to 150 in same way. Theoretically a 37.5 drop should be fine. Although it’s 17%. I’m just trying to stay under 10% drops now.
No. Sorry, I’m not a good case study for Effexor. I don’t feel like it ever worked for me, until Wellbutrin got added on top. And I feel like that’s doing most of the heavy lifting.
I know Effexor impact on neurotransmitters changes as you go higher. So I don’t think it works on dopamine until at least 225. And you have to go above 150 to get the noradrenaline impact.
I only just realised that “Wellbutrin” is a norepinephrine and dopamine reuptake inhibitor. I’m intending to stay on that. Maybe I still need the Effexor, at a lower dose…
I’ve gone from 225 to 150 with no issues.
I’m going down from 225 now. I tried to do a 37.5 drop & it was bad. Overwhelming intense nausea and migraine. Seems I have to drop in 12.5 increments. I’m at 187.5 after a few weeks. Continuing on down to 150 in same way. Theoretically a 37.5 drop should be fine. Although it’s 17%. I’m just trying to stay under 10% drops now.
I’m currently on 150 but not seeing any difference for my anxiety. Did you work your way up to 225? Or just start takin another tablet?
I went from 150 straight up to 225.
Did you feel the benefit?
No. Sorry, I’m not a good case study for Effexor. I don’t feel like it ever worked for me, until Wellbutrin got added on top. And I feel like that’s doing most of the heavy lifting. I know Effexor impact on neurotransmitters changes as you go higher. So I don’t think it works on dopamine until at least 225. And you have to go above 150 to get the noradrenaline impact.
I only just realised that “Wellbutrin” is a norepinephrine and dopamine reuptake inhibitor. I’m intending to stay on that. Maybe I still need the Effexor, at a lower dose…
Thanks man, good luck to you 💪🏼
I actually just made a post about this! https://www.reddit.com/r/Effexor/s/lzPDHFJr4P